Showing posts with label brain research. Show all posts
Showing posts with label brain research. Show all posts

Friday, September 11, 2020

SEARCHING FOR THE OPTIMAL WORD

As authors, we all know by now how to work the “search engine optimization” game. That is, we’ve learned how to ensure that when someone searches for us or our books on Google (or some other Internet search engine), they find our websites and titles first, and not some random schmoe with a similar sounding name or domain. As I explained in a recent post, keywords work the same way to direct searches for our books on Amazon. Assign the right keywords to your titles and readers find your books a lot faster.

Scientists at the National Institutes of Health/National Institute of Neurological Disorders and Stroke (NINDS) have discovered in a new study that our minds search for words in a way that is very similar to SEO, giving preference to words with similar meanings to create a kind of linguistic network. Some words are easier to remember because they are semantically linked, leading to areas of high traffic in the network, while others are harder to remember because they have fewer meaningful links, leaving them on the “outskirts.” It’s as if some words show up first in the Google search and others show up on page five—or 100.

The right words are easy to remember--apparently.

"We found that some words are much more memorable than others. Our results support the idea that our memories are wired into neural networks and that our brains search for these memories, just the way search engines track down information on the internet," said Weizhen (Zane) Xie, Ph.D., a cognitive psychologist and post-doctoral fellow at NINDS, who led the study published in Nature Human Behaviour. "We hope that these results can be used as a roadmap to evaluate the health of a person's memory and brain."

The study focused on common words like “pig,” “tank,” and “door,” which turned out to be much more memorable than other common words like “cat,” “street” and “stair.” The researchers used brain wave recordings, memory tests and surveys of billions of words from a variety of sources for their work, the idea for which arose out of small study of epilepsy patients with intractable seizures. In that study, a team of scientists led by Dr. Kareem Zaghloul at NINDS used a simple test for recalling pairs of words to observe how neural circuits in the brain record and replay memories. They saw that some of the 300 pairs of words they used were easier for their subjects to recall than others.

At first, the team dismissed the results. Yet when researchers tried again with the same words in different pairs, they discovered the same words gave their subjects trouble no matter how they were paired. The scientists remained skeptical, hypothesizing that differences in the subjects’ backgrounds might yield a different “relationship” to the words, giving them more or less “weight.”

But a larger study of 2623 healthy volunteers on an online crowdsourcing site yielded similar results, proving that the small, epilepsy study was no fluke.  

Then in a moment of serendipity at a Christmas party, Xie met Wilma Bainbridge, Ph.D., an assistant professor in the department of psychology at the University of Chicago, who, at the time was working as a post-doctoral fellow at the NIH's National Institute of Mental Health (NIMH). Bainbridge had written a paper on the theory that some faces are inherently more memorable than others.  

"Our exciting finding is that there are some images of people or places that are inherently memorable for all people, even though we have each seen different things in our lives," said Bainbridge. "And if image memorability is so powerful, this means we can know in advance what people are likely to remember or forget."

Even though Bainbridge’s theory—the Search for Associative Memory model—had only been applied to images, Xie thought it could be applied to the work he and Zaghloul had been doing with words. “We thought one way to understand the results of the word pair tests was to apply network theories for how the brain remembers past experiences," said Xie. “In this case, memories of the words we used look like internet or airport terminal maps, with the more memorable words appearing as big, highly trafficked spots connected to smaller spots representing the less memorable words. The key to fully understanding this was to figure out what connects the words."

The researchers had to write a new computer model to do this, and, in doing so, found some of their simplest explanations for why certain words were more memorable didn’t account for their results. It wasn’t the number of times the words appeared in sentences that made them memorable, for example, or the “concreteness” of their definitions. It was, in fact, the semantic links—that is, the meaningful connections—attributed to the words that made them more memorable. (Though—to pause for an editorial comment here—how “pig” could have more semantic impact than “cat” is a mystery to me.) The more semantic links, the heavier the network “traffic” through the word in the brain.

To the scientists this is vital to the understanding of how the brain works and can lead to better medical intervention in the future. For me as a writer, though, not only am I picking up all kinds of plot bunnies for my telepathic Thrane aliens, but I’m also working overtime to figure out which words might have the best neural connections for my next best-selling title. Without somehow resorting to the use of “pig.”

Cheers, Donna

*Information for this post provided from: "Why some words may be more memorable than others," NIH/National Institute of Neurological Disorders and Stroke, as reported in Science Daily.com, June 29, 2020. https://www.sciencedaily.com/releases/2020/06/200629120204.htm

Friday, March 16, 2018

BRAIN RESEARCH GOES BEYOND THE PALE



And now for some news from the world of Technology Beyond Good Sense.
According to George Dvorsky at Futurism, scientists at MIT and 21st Century Medicine have developed a new mammalian brain preservation technique that makes it possible to save the information stored within the structure of the brain—memories, for example, or sensory data—after the death of brain tissue. The technique, called Aldehyde-Stabilized Cryopreservation (ASC), has so far been tested on rabbits and pigs, and is promising enough to have earned its developers a research grant which would help them take the first steps toward long-term human brain biostasis.

Though the scientists hasten to add that they are nowhere near that point now, but results of their studies have been independently verified and published in the scientific journal Cryobiology. One of the scientists, Robert McIntyre of MIT, has gone so far as to establish a private company with the stated goal of developing a technology

to preserve your brain well enough to keep all its memories intact: from that great chapter of your favorite book to the feeling of cold winter air, baking an apple pie, or having dinner with your friends and family. We believe that within the current century it will be feasible to digitize this information and use it to recreate your consciousness.

Am I the only one who finds this a little creepy? Especially when you learn the ASC technique doesn’t actually preserve the brain itself, but turns the thing into a kind of “plasticized object,” an object, we can only hope, retains the relevant information contained in the grey matter it, um, replaces during the cryogenic process.



Dvorsky puts it this way: 

For those of you thinking this is a path towards immortality, you may be in for a profound disappointment. Technical hurdles aside, the ASC approach doesn’t guarantee a continuity of consciousness. As mentioned, [euthanasia to preserve the brain before death by terminal illness} is a form of destructive preservation, where biological matter is basically transmutated into a temporary storage device. While your memories and personality stand a chance of revival, your seat of consciousness will likely be obliterated for all time. Brain preservation in this manner is thus a form of suicide, but with knowledge that a digital “copy” of you may live to see another day.

Okay, wow. You can replicate your personality and memories, but not your actual consciousness? And where, exactly, does that consciousness reside? Certainly not in the brain tissue, if I remember my Sunday school lessons correctly. (And I think Buddha, Muhammed, the Taoists, priests and shamans of multiple faiths and even some wiccans would agree with those lessons.) And what good is retaining your memories and personality, if your consciousness is somewhere else?

Of course, plot bunnies are hopping all over my consciousness at this point. The simplest and most obvious use of this technology would be military (or should I say military intelligence). Your spy dies in the field? No problem! Just “download” his brain to get that vital information! Combine this tech with cloning and you’ve got any number of copies of James Bond—all dispensable.

A frightening idea. And, now one that is ultimately possible.

Cheers, Donna

Information for this post taken from “New Brain Preservation Techniques could be a Path to Mind Uploading, by George Dvorsky, Futurism, March 14, 2018, https://gizmodo.com/new-brain-preservation-technique-could-be-a-path-to-min-1823741147